Crescel Skin Renewal Cream - 3.4 oz

The Scientific Essentials-

A Groundbreaking Integration of Natural Processes and New Concepts

Pioneering Proprietary Microemulsion Technology

Crescel’s unique microemulsion technology enables delivery of a proprietary combination of botanical ingredients (a spectrum of extracts from aloe barbadensis and oat kernel, i.e., avena sativa, oil) deep into the skin for continuous anti-inflammatory and moisturization activity. Although these botanicals have been widely recognized for their anti-inflammatory and skin barrier-repair properties, Crescel’s proprietary formula elevates these benefits to a new level of efficacy. The technology is designed to preserve their biological activities when they are combined and produce novel synergistic activity. Additionally, Crescel maintains the physiological pH of the skin and is thus unbuffered, and it incorporates hydrophilic and hydrophobic components consonant with the skin cells and mitochondria. 

Easy! Apply Twice Daily.

Follow this simple routine once in the morning, once in the evening. Gently clean the entire area to be treated with water (and mild soap, if available), then pat it dry—no rubbing. (If the skin is badly damaged, talk with your doctor about the best way to clean it.) Then gently rub Crescel cream into the affected skin area, and be sure to include the normal-looking skin surrounding it.

For external use only.

No Side Effects. No Compromises.

A thorough study was done in 2012 by one of the leading organizations specializing in this kind of research. The aim was to see how likely Crescel is to irritate or sensitize people’s skin. Irritation is the production of reversible inflammatory damage to the skin. Sensitization refers to setting off an allergic reaction. When that happens, the first application to the skin sets up the components of an allergic reaction. Then every future application sets it into motion. Crescel’s results lived up to Passalacqua’s determination to create a powerfully therapeutic product that is also as gentle to the skin as possible.

The study group included 55 people with normal skin. There were men and women, and their broad age range (from 18 to 70 years old) spanned from adolescents to seniors. The irritation phase was evaluated first. Because the signs of irritation can take a little time to appear, this involved a brief series of alternate-day applications at the same skin location. The skin was evaluated the day after each new application and given a score, with “0” indicating the complete absence of irritation. Then after a 2-week rest from Crescel, the cream was applied in a different skin location to see if an allergic reaction appeared there. In the evaluation scores the next day, “0” indicated the complete absence of allergic indicators. And the results could not have been better. The scores for all 55 study participants were uniformly “0” for both irritation and sensitization. As Passalacqua intended, Crescel lacks even the most minimal negative side effects.

Clinical Study Conducted by World-Renowned Dermatologist Demonstrates Crescel’s Safety, Tolerability, and Statistically Significant Clinical Benefit for Rosacea

Rosacea affects more than 415 million people worldwide and is known for highly reactive, treatment-sensitive skin. In a 4-week clinical tolerance study conducted by a world-renowned dermatologist involving 30 rosacea patients, Crescel demonstrated exceptional safety and tolerability, with no reported adverse reactions—including no dryness, peeling, redness, swelling, stinging, itching, or burning.

Patients also experienced statistically significant early improvements before the study concluded, including a 38% reduction in facial redness (erythema), a 42% reduction in flushing severity, and a 41% reduction in flushing frequency. Participants additionally reported less dryness, itching, and stinging. These findings met the National Rosacea Society’s criteria for its Seal of Acceptance and position Crescel as a uniquely gentle, first-line therapeutic option for rosacea management.